Use of a Patch Containing Heat-Labile Toxin From Escherichia Coli Against Travellers’ Diarrhoea: A Phase II, Randomised, Double-Blind, Placebo-Controlled Field Trial

Enterotoxigenic Escherichia coli (ETEC) is a major cause of travellers' diarrhoea. We investigated the rate of diarrhoea attacks, safety, and feasibility of a vaccine containing heat-labile enterotoxin (LT) from ETEC delivered to the skin by patch in travellers to Mexico and Guatemala.

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